SCG5 antibody (AA 90-170)

Catalog No. ABIN7227106

The Rabbit Polyclonal anti-SCG5 antibody (ABIN7227106) specifically detects SCG5 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SCG5 antibody (AA 90-170) (ABIN7227106)

Target: SCG5 (Secretogranin V (7B2 Protein) (SCG5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCG5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SCG5 Antibody

Binding Specificity: AA 90-170

Purpose: Rabbit Anti-7B2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of 7B2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human 7B2 protein at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SCG5

Target: SCG5 (Secretogranin V (7B2 Protein) (SCG5))

Alternative Name: 7B2

Background: Neuroendocrine protein 7B2, Pituitary polypeptide, Secretogranin V, Secretogranin-5, Secretory granule endocrine protein ISCG5 (Secretogranin V) is a Protein Coding gene. Diseases associated with SCG5 include Hereditary Mixed Polyposis Syndrome 1 and Hereditary Mixed Polyposis Syndrome. SCG5 encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins, including proteins that are associated with neurodegenerative and metabolic disease. The encoded protein may be best known for its role in the trafficking and activation of prohormone convertase PC2. Phosphorylation of the encoded protein has been shown to have an inhibitory effect on its chaperone function.

Molecular Weight: 23kD

Gene ID: 6447

UniProt: P05408