NEUROD1 antibody (AA 154-356)

Catalog No. ABIN7161282

The Rabbit Polyclonal anti-NEUROD1 antibody has been validated for WB, ELISA and IF. It is suitable to detect NEUROD1 in samples from Human.

Quick Overview for NEUROD1 antibody (AA 154-356) (ABIN7161282)

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEUROD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-NEUROD1 Antibody

Binding Specificity: AA 154-356

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Neurogenic differentiation factor 1 protein (154-356AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:2000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NEUROD1

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Alternative Name: NEUROD1

Background:

Background: Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5\\\'-CANNTG-3\\\'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).

Aliases: atonal antibody, basic helix loop helix transcription factor antibody, BETA 2 antibody, Beta cell E box transactivator 2 antibody, BETA2 antibody, BHF 1 antibody, BHF1 antibody, bHLHa3 antibody, class A basic helix loop helix protein 3 antibody, Class A basic helix-loop-helix protein 3 antibody, MODY 6 antibody, MODY6 antibody, NDF1_HUMAN antibody, NeuroD antibody, NeuroD1 antibody, Neurogenic differentiation 1 antibody, Neurogenic differentiation factor 1 antibody, neurogenic helix loop helix protein NEUROD antibody, Neuronal differentiation 1 antibody

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis