NLRC4 antibody (AA 1-250)

Catalog No. ABIN7161654

The Rabbit Polyclonal anti-NLRC4 antibody has been validated for IHC and ELISA. It is suitable to detect NLRC4 in samples from Human.

Quick Overview for NLRC4 antibody (AA 1-250) (ABIN7161654)

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRC4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-NLRC4 Antibody

Binding Specificity: AA 1-250

Cross-Reactivity: Human

Purification: Antigen Affinity purified

Immunogen: Recombinant Human NLR family CARD domain-containing protein 4 protein (1-250AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NLRC4

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Alternative Name: NLRC4

Background:

Background: Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis.

Aliases: and NACHT-containing protein antibody, CARD 12 antibody, CARD antibody, CARD LRR and NACHT containing protein 1 antibody, CARD LRR and NACHT containing protein antibody, CARD12 antibody, Caspase recruitment domain containing protein 12 antibody, Caspase recruitment domain family member 12 antibody, Caspase recruitment domain-containing protein 12 antibody, CLAN 1 antibody, CLAN A antibody, CLAN antibody, CLAN B antibody, CLAN C antibody, CLAN D antibody, Clan protein antibody, CLAN1 antibody, CLANA antibody, CLANB antibody, CLANC antibody, CLAND antibody, CLR 2.1 antibody, CLR2.1 antibody, ICE protease activating factor antibody, Ice protease-activating factor antibody, Ipaf antibody, LRR antibody, NLR family CARD domain containing 4 antibody, NLR family CARD domain-containing protein 4 antibody, NLRC 4 antibody, NLRC4 antibody, NLRC4_HUMAN antibody, NOD like receptor C4 antibody, Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 4 antibody, UNQ6189/PRO20215 antibody

UniProt: Q9NPP4

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome