NUP153 antibody (AA 657-880) (Biotin)

Catalog No. ABIN7161820

This anti-NUP153 antibody is a Rabbit Polyclonal antibody detecting NUP153 in ELISA. Suitable for Human.

Quick Overview for NUP153 antibody (AA 657-880) (Biotin) (ABIN7161820)

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP153 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-NUP153 Antibody (Biotin)

Binding Specificity: AA 657-880

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Nuclear pore complex protein Nup153 protein (657-880AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NUP153

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Alternative Name: NUP153

Background:

Background: Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus, in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC).

Aliases: 153 kDa nucleoporin antibody, HNUP153 antibody, N153 antibody, NU153_HUMAN antibody, Nuclear pore complex protein hnup153 antibody, Nuclear pore complex protein Nup153 antibody, Nucleoporin 153 kDa antibody, Nucleoporin Nup153 antibody, Nup 153 antibody, Nup153 antibody

UniProt: P49790

Pathways: Protein targeting to Nucleus