Osteocrin antibody (AA 28-133) (HRP)
Quick Overview for Osteocrin antibody (AA 28-133) (HRP) (ABIN7162316)
Target
See all Osteocrin (OSTN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 28-133
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Osteocrin protein (28-133aa)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Osteocrin (OSTN)
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Alternative Name
- OSTN
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Background
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Background: Hormone that acts as a regulator of dendritic growth in the developing cerebral cortex in response to sensory experience (PubMed:27830782). Induced in the brain following membrane depolarization and inhibits dendritic branching in neurons of the developing cortex (PubMed:27830782). Probably acts by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity).
Aliases: Osteocrin (Musclin) [Cleaved into: Processed Osteocrin], OSTN
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UniProt
- P61366
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Pathways
- Hormone Activity
Target
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