P2RX7 antibody (AA 110-247) (FITC)

Catalog No. ABIN7162451

This Rabbit Polyclonal antibody specifically detects P2RX7 . It exhibits reactivity toward Human.

Quick Overview for P2RX7 antibody (AA 110-247) (FITC) (ABIN7162451)

Target: P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RX7 antibody is conjugated to FITC

Application: Please inquire

Product Details anti-P2RX7 Antibody (FITC)

Binding Specificity: AA 110-247

Purpose: P2RX7 Antibody, FITC conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human P2X purinoceptor 7 protein (110-247AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for P2RX7

Target: P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))

Alternative Name: P2RX7

Background:

Background: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.

Aliases: ATP receptor antibody, P2rx7 antibody, P2RX7_HUMAN antibody, P2X purinoceptor 7 antibody, P2X7 antibody, P2Z receptor antibody, Purinergic receptor antibody, purinergic receptor P2X, ligand gated ion channel, 7 antibody

UniProt: Q99572

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis