Perforin 1 antibody (AA 22-554)

Catalog No. ABIN7162873

This anti-Perforin 1 antibody is a Rabbit Polyclonal antibody detecting Perforin 1 in ELISA. Suitable for Human.

Quick Overview for Perforin 1 antibody (AA 22-554) (ABIN7162873)

Target: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Perforin 1 antibody is un-conjugated

Application: ELISA

Product Details anti-Perforin 1 Antibody

Binding Specificity: AA 22-554

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Perforin-1 protein (22-554AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Perforin 1

Target: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Alternative Name: PRF1

Background:

Background: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

Aliases: Cytolysin antibody, FLH2 antibody, HPLH2 antibody, Lymphocyte pore-forming protein antibody, P1 antibody, PERF_HUMAN antibody, perforin 1 (pore forming protein) antibody, Perforin 1 antibody, Perforin-1 antibody, PFP antibody, PGFL antibody, PIGF antibody, PIGF-2 antibody, PLGF antibody, Pore forming protein antibody, prf1 antibody, SHGC-10760 antibody

UniProt: P14222

Pathways: Apoptosis, Caspase Cascade in Apoptosis