PREX1 antibody (AA 1-44)

Catalog No. ABIN7163177

This Rabbit Polyclonal antibody specifically detects PREX1 in ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for PREX1 antibody (AA 1-44) (ABIN7163177)

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PREX1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PREX1 Antibody

Binding Specificity: AA 1-44

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (1-44AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PREX1

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Alternative Name: PREX1

Background:

Background: Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.

Aliases: 4 antibody, 5)-dependent Rac exchanger 1 antibody, KIAA1415 antibody, OTTHUMP00000031228 antibody, P REX1 antibody, P Rex1 protein like antibody, P-Rex1 antibody, Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchange factor 1 antibody, Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 antibody, Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 protein antibody, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein antibody, Prex1 antibody, PREX1_HUMAN antibody, PtdIns(3 antibody, PtdIns(3,4,5) dependent Rac exchanger 1 antibody, SET domain containing 6 antibody, Setd6 antibody

UniProt: Q8TCU6

Pathways: Regulation of Actin Filament Polymerization