Kv1.6/KCNA6 antibody (AA 1-171)

Catalog No. ABIN7163953

The Rabbit Polyclonal anti-Kv1.6/KCNA6 antibody (ABIN7163953) specifically detects Kv1.6/KCNA6 in ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for Kv1.6/KCNA6 antibody (AA 1-171) (ABIN7163953)

Target: Kv1.6/KCNA6 (KCNA6) (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 6 (KCNA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kv1.6/KCNA6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-Kv1.6/KCNA6 Antibody

Binding Specificity: AA 1-171

Purpose: KCNA6 Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Potassium voltage-gated channel subfamily A member 6 protein (1-171AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Kv1.6/KCNA6

Target: Kv1.6/KCNA6 (KCNA6) (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 6 (KCNA6))

Alternative Name: KCNA6

Background:

Background: Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient (PubMed:2347305, PubMed:14575698). The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (PubMed:2347305, PubMed:14575698). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA6, and possibly other family members as well, channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation. Homotetrameric channels display rapid activation and slow inactivation (PubMed:2347305).

Aliases: HBK 2 antibody, HBK2 antibody, Human brain potassium channel 2 antibody, KCNA 6 antibody, Kcna6 antibody, KCNA6_HUMAN antibody, Potassium voltage gated channel shaker related subfamily member 6 antibody, Potassium voltage gated channel subfamily A member 6 antibody, Potassium voltage-gated channel subfamily A member 6 antibody, Voltage gated potassium channel protein Kv1.6 antibody, Voltage gated potassium channel subunit Kv1.6 antibody, Voltage-gated potassium channel HBK2 antibody, Voltage-gated potassium channel subunit Kv1.6 antibody

UniProt: P17658