PZP antibody (AA 472-821)

Catalog No. ABIN7164226

This anti-PZP antibody is a Rabbit Polyclonal antibody detecting PZP in ELISA. Suitable for Human.

Quick Overview for PZP antibody (AA 472-821) (ABIN7164226)

Target: PZP (Pregnancy Zone Protein (PZP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PZP antibody is un-conjugated

Application: ELISA

Product Details anti-PZP Antibody

Binding Specificity: AA 472-821

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Pregnancy zone protein (472-821AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PZP

Target: PZP (Pregnancy Zone Protein (PZP))

Alternative Name: PZP

Background:

Background: Is able to inhibit all four classes of proteinases by a unique \\\'trapping\\\' mechanism. This protein has a peptide stretch, called the \\\'bait region\\\' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Aliases: PZP antibody, CPAMD6 antibody, Pregnancy zone protein antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6 antibody

UniProt: P20742