PZP antibody (AA 1301-1350)

Catalog No. ABIN7230862

The Rabbit Polyclonal anti-PZP antibody (ABIN7230862) specifically detects PZP in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for PZP antibody (AA 1301-1350) (ABIN7230862)

Target: PZP (Pregnancy Zone Protein (PZP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PZP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PZP Antibody

Binding Specificity: AA 1301-1350

Purpose: Rabbit Anti-PZP Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PZP protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PZP protein at AA range: 1301-1350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PZP

Target: PZP (Pregnancy Zone Protein (PZP))

Alternative Name: PZP

Background: Pregnancy zone protein, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Molecular Weight: 163kD

Gene ID: 5858

UniProt: P20742