PARL antibody (AA 1-170)

Catalog No. ABIN7164273

The Rabbit Polyclonal anti-PARL antibody has been validated for WB, ELISA and IHC. It is suitable to detect PARL in samples from Human.

Quick Overview for PARL antibody (AA 1-170) (ABIN7164273)

Target: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PARL Antibody

Binding Specificity: AA 1-170

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Presenilins-associated rhomboid-like protein, mitochondrial protein (1-170AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PARL

Target: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Alternative Name: PARL

Background:

Background: Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain.

Aliases: Mitochondrial intramembrane cleaving protease PARL antibody, Mitochondrial intramembrane-cleaving protease PARL antibody, P-beta antibody, parl antibody, PARL_HUMAN antibody, Pbeta antibody, presenilin associated rhomboid-like antibody, Presenilins associated rhomboid-like protein antibody, PRO2207 antibody, PSARL antibody, PSARL1 antibody, PSENIP2 antibody, RHBDS1 antibody, Rhomboid 7 homolog 1 antibody

UniProt: Q9H300

Pathways: Autophagy