PITRM1 antibody (AA 758-1037)

Catalog No. ABIN7164274

This anti-PITRM1 antibody is a Rabbit Polyclonal antibody detecting PITRM1 in WB, IHC and ELISA. Suitable for Human.

Quick Overview for PITRM1 antibody (AA 758-1037) (ABIN7164274)

Target: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PITRM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PITRM1 Antibody

Binding Specificity: AA 758-1037

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Presequence protease, mitochondrial protein (758-1037AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PITRM1

Target: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Alternative Name: PITRM1

Background:

Background: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

Aliases: hMP1 antibody, hPreP antibody, KIAA1104 antibody, Metalloprotease 1 antibody, MGC138192 antibody, MGC141929 antibody, mitochondrial antibody, MP1 antibody, Pitrilysin metallopeptidase 1 antibody, Pitrilysin metalloproteinase 1 antibody, PITRM 1 antibody, PITRM1 antibody, PreP antibody, PreP peptidasome antibody, PREP_HUMAN antibody, Presequence protease antibody, Presequence protease mitochondrial antibody

UniProt: Q5JRX3

Pathways: PI3K-Akt Signaling, SARS-CoV-2 Protein Interactome