Epiregulin antibody (AA 144-160) (Biotin)

Catalog No. ABIN7164651

The Rabbit Polyclonal anti-Epiregulin antibody has been validated for ELISA. It is suitable to detect Epiregulin in samples from Human.

Quick Overview for Epiregulin antibody (AA 144-160) (Biotin) (ABIN7164651)

Target: Epiregulin (EREG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epiregulin antibody is conjugated to Biotin

Application: ELISA

Product Details anti-Epiregulin Antibody (Biotin)

Binding Specificity: AA 144-160

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Proepiregulin protein (144-160aa)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Epiregulin

Target: Epiregulin (EREG)

Alternative Name: EREG

Background:

Background: Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9419975). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357).

Aliases: Proepiregulin [Cleaved into: Epiregulin (EPR)], EREG

UniProt: O14944

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation