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HBEGF antibody (AA 63-148)

HBEGF Reactivity: Human ELISA, IF, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7164700
$328.90
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  • Target See all HBEGF Antibodies
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    Binding Specificity
    • 15
    • 11
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 63-148
    Reactivity
    • 47
    • 10
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 44
    • 6
    Rabbit
    Clonality
    • 43
    • 7
    Polyclonal
    Conjugate
    • 22
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HBEGF antibody is un-conjugated
    Application
    • 20
    • 16
    • 13
    • 13
    • 10
    • 9
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Proheparin-binding EGF-like growth factor protein (63-148AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    Alternative Name
    HBEGF (HBEGF Products)
    Synonyms
    hbegf antibody, zgc:165443 antibody, HBEGF antibody, zgc:175091 antibody, DTR antibody, DTS antibody, DTSF antibody, HEGFL antibody, Dtr antibody, GFHB antibody, Hb-egf antibody, Hegfl antibody, AW047313 antibody, Dts antibody, HB-EGF antibody, heparin-binding EGF-like growth factor b antibody, heparin binding EGF like growth factor antibody, Heparin-binding EGF-like growth factor antibody, heparin-binding EGF-like growth factor a antibody, heparin-binding EGF-like growth factor antibody, hbegfb antibody, HBEGF antibody, hbegf antibody, hbegfa antibody, Hbegf antibody
    Background

    Background: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

    Aliases: diphtheria toxin receptor (heparin-binding EGF-like growth factor) antibody, diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor) antibody, Diphtheria toxin receptor antibody, DT R antibody, DT-R antibody, DTR antibody, DTS antibody, DTSF antibody, HB-EGF antibody, HBEGF antibody, HBEGF_HUMAN antibody, HEGFL antibody, Heparin binding EGF like growth factor antibody, Heparin binding epidermal growth factor antibody, Heparin binding epidermal growth factor like growth factor antibody, Heparin-binding EGF-like growth factor antibody, Proheparin binding EGF like growth factor antibody

    UniProt
    Q99075
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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