PRMT2 antibody (AA 1-300)

Catalog No. ABIN7165066

This anti-PRMT2 antibody is a Rabbit Polyclonal antibody detecting PRMT2 in WB, IHC and ELISA. Suitable for Human.

Quick Overview for PRMT2 antibody (AA 1-300) (ABIN7165066)

Target: PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PRMT2 Antibody

Binding Specificity: AA 1-300

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Protein arginine N-methyltransferase 2 protein (1-300AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PRMT2

Target: PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))

Alternative Name: PRMT2

Background:

Background: Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation.

Aliases: ANM2_HUMAN antibody, EC 2.1.1. antibody, histone arginine N methyltransferase PRMT2 antibody, Histone-arginine N-methyltransferase PRMT2 antibody, HMT 1 antibody, HMT1 (hnRNP methyltransferase S. cerevisiae) like 1 antibody, HMT1 antibody, HMT1 hnRNP methyltransferase like 1 antibody, hnRNP methyltransferase (S. cerevisiae) like 1 antibody, hnRNP methyltransferase like 1 antibody, Hrmt1l1 antibody, MGC111373 antibody, PRMT 2 antibody, PRMT2 alpha antibody, prmt2 antibody, PRMT2 beta antibody, PRMT2 gamma antibody, PRMT2 protein antibody, PRMT2L2 antibody, Protein arginine methyltransferase 2 antibody, Protein arginine N methyltransferase 2 antibody, Protein arginine N-methyltransferase 2 antibody, Zf2 antibody

UniProt: P55345

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding