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HOOK3 antibody (AA 357-455)

HOOK3 Reactivity: Human ELISA, IHC, IP, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7165641
$328.90
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  • Target See all HOOK3 Antibodies
    HOOK3 (Hook Homolog 3 (HOOK3))
    Binding Specificity
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 357-455
    Reactivity
    • 23
    • 14
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 19
    • 4
    Rabbit
    Clonality
    • 21
    • 2
    Polyclonal
    Conjugate
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HOOK3 antibody is un-conjugated
    Application
    • 13
    • 8
    • 4
    • 4
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Protein Hook homolog 3 protein (357-455AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IP:1:200-1:2000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    HOOK3 (Hook Homolog 3 (HOOK3))
    Alternative Name
    HOOK3 (HOOK3 Products)
    Synonyms
    5830454D03Rik antibody, AI317159 antibody, E330005F07Rik antibody, HK3 antibody, hook3 antibody, hook microtubule-tethering protein 3 antibody, hook microtubule tethering protein 3 antibody, hook microtubule-tethering protein 3 L homeolog antibody, Hook3 antibody, HOOK3 antibody, hook3.L antibody
    Background

    Background: Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).

    Aliases: FLJ31058 antibody, h-hook3 antibody, hHK3 antibody, HK3 antibody, hook3 antibody, HOOK3_HUMAN antibody, OTTHUMP00000229200 antibody, Protein Hook homolog 3 antibody

    UniProt
    Q86VS8
    Pathways
    Stem Cell Maintenance, Maintenance of Protein Location
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