RP2 antibody (AA 1-350)
Quick Overview for RP2 antibody (AA 1-350) (ABIN7166332)
Target
See all RP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-350
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Protein XRP2 protein (1-350AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))
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Alternative Name
- RP2
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Background
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Background: Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.
Aliases: RP2 antibody, Protein XRP2 antibody
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UniProt
- O75695
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Pathways
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
Target
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