MCF2 antibody (AA 705-925)

Catalog No. ABIN7166480

This Rabbit Polyclonal antibody specifically detects MCF2 in ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for MCF2 antibody (AA 705-925) (ABIN7166480)

Target: MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCF2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MCF2 Antibody

Binding Specificity: AA 705-925

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Proto-oncogene DBL protein (705-925AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MCF2

Target: MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

Alternative Name: MCF2

Background:

Background: Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.

Aliases: MCF2 antibody, DBLProto-oncogene DBL antibody, Proto-oncogene MCF-2) [Cleaved into: MCF2-transforming protein, DBL-transforming protein] antibody

UniProt: P10911