MAS1 antibody (AA 246-325)

Catalog No. ABIN7166484

The Rabbit Polyclonal anti-MAS1 antibody has been validated for IHC and ELISA. It is suitable to detect MAS1 in samples from Human.

Quick Overview for MAS1 antibody (AA 246-325) (ABIN7166484)

Target: MAS1 (MAS1 Oncogene (MAS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAS1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-MAS1 Antibody

Binding Specificity: AA 246-325

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Proto-oncogene Mas protein (246-325AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MAS1

Target: MAS1 (MAS1 Oncogene (MAS1))

Alternative Name: MAS1

Background:

Background: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.

Aliases: MAS antibody, MAS proto oncogene antibody, Mas-related G protein-coupled receptor A antibody, MAS_HUMAN antibody, Mas1 antibody, MAS1 oncogene antibody, MAS1 proto-oncogene, G protein-coupled receptor antibody, MGRA antibody, Proto-oncogene Mas antibody

UniProt: P04201

Pathways: ACE Inhibitor Pathway, Regulation of Carbohydrate Metabolic Process