Rabenosyn 5 antibody (AA 201-500)

Catalog No. ABIN7167013

Product Details anti-Rabenosyn 5 Antibody

Target: Rabenosyn 5 (ZFYVE20) (Zinc Finger, FYVE Domain Containing 20 (ZFYVE20))

Binding Specificity: AA 201-500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Rabenosyn 5 antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Rabenosyn-5 protein (201-500AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Rabenosyn 5

Target: Rabenosyn 5 (ZFYVE20) (Zinc Finger, FYVE Domain Containing 20 (ZFYVE20))

Alternative Name: RBSN (ZFYVE20 Products)

Synonyms: zfyve20 antibody, Rabenosyn-5 antibody, 5330426D11Rik antibody, rabenosyn, RAB effector antibody, si:dkey-187a12.4 antibody, rabenosyn-5 antibody, RBSN antibody, si:dkey-187a12.4 antibody, CpipJ_CPIJ003819 antibody, rbsn antibody, Rbsn antibody

Background:

Background: Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) (PubMed:11062261, PubMed:11788822, PubMed:15020713). Plays a role in the recycling of transferrin receptor to the plasma membrane (PubMed:22308388).

Aliases: 110 kDa protein antibody, FYVE finger containing Rab5 effector protein Rabenosyn 5 antibody, FYVE finger-containing Rab5 effector protein rabenosyn-5 antibody, Rabenosyn-5 antibody, RBNS5_HUMAN antibody, Zfyve20 antibody, zinc finger FYVE domain containing 20 antibody, Zinc finger FYVE domain-containing protein 20 antibody

UniProt: Q9H1K0

Pathways: Toll-Like Receptors Cascades