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RRAGA antibody (AA 1-247) (Biotin)

RRAGA Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7167206
  • Target See all RRAGA Antibodies
    RRAGA (Ras-Related GTP Binding A (RRAGA))
    Binding Specificity
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-247
    Reactivity
    • 25
    • 12
    • 12
    • 1
    Human
    Host
    • 25
    Rabbit
    Clonality
    • 24
    • 1
    Polyclonal
    Conjugate
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RRAGA antibody is conjugated to Biotin
    Application
    • 12
    • 10
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Ras-related GTP-binding protein A protein (1-247AA)
    Isotype
    IgG
    Top Product
    Discover our top product RRAGA Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    RRAGA (Ras-Related GTP Binding A (RRAGA))
    Alternative Name
    RRAGA (RRAGA Products)
    Synonyms
    FIP-1 antibody, FIP1 antibody, RAGA antibody, 1300010C19Rik antibody, AI255374 antibody, Raga antibody, Ras related GTP binding A antibody, Ras-related GTP binding A antibody, RRAGA antibody, Rraga antibody
    Background

    Background: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

    Aliases: Adenovirus E3 14.7 kDa-interacting protein 1 antibody, FIP-1 antibody, Rag A antibody, RagA antibody, Ras-related GTP-binding protein A antibody, RRAGA antibody, RRAGA_HUMAN antibody

    UniProt
    Q7L523
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