RALB antibody (AA 1-206)

Catalog No. ABIN7167394

The Rabbit Polyclonal anti-RALB antibody (ABIN7167394) specifically detects RALB in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for RALB antibody (AA 1-206) (ABIN7167394)

Target: RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RALB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RALB Antibody

Binding Specificity: AA 1-206

Purpose: RALB Antibody

Cross-Reactivity: Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ras-related protein Ral-B protein (1-206AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RALB

Target: RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))

Alternative Name: RALB

Background:

Background: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. Required for suppression of apoptosis.

Aliases: 5730472O18Rik antibody, dRalb antibody, GTP binding protein antibody, Ralb antibody, RALB_HUMAN antibody, RAS like protein B antibody, RAS like proto oncogene B antibody, Ras related GTP binding protein B antibody, Ras-related protein Ral-B antibody, v ral simian leukemia viral oncogene homolog B (ras related GTP binding protein) antibody, v ral simian leukemia viral oncogene homolog B (ras related) antibody, V ral simian leukemia viral oncogene homolog B antibody

UniProt: P11234

Pathways: Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events