RGS7 antibody (AA 1-300)

Catalog No. ABIN7167620

This Rabbit Polyclonal antibody specifically detects RGS7 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for RGS7 antibody (AA 1-300) (ABIN7167620)

Target: RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-RGS7 Antibody

Binding Specificity: AA 1-300

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Regulator of G-protein signaling 7 protein (1-300AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RGS7

Target: RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

Alternative Name: RGS7

Background:

Background: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509). May play a role in synaptic vesicle exocytosis (PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PubMed:15897264).

Aliases: RGS7 antibody, Regulator of G-protein signaling 7 antibody, RGS7 antibody

UniProt: P49802

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling