RHOB antibody (AA 1-196)

Catalog No. ABIN7168018

This anti-RHOB antibody is a Rabbit Polyclonal antibody detecting RHOB in ELISA and IF. Suitable for Human.

Quick Overview for RHOB antibody (AA 1-196) (ABIN7168018)

Target: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHOB antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-RHOB Antibody

Binding Specificity: AA 1-196

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Rho-related GTP-binding protein RhoB protein (1-196AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RHOB

Target: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Alternative Name: RHOB

Background:

Background: Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

Aliases: Aplysia RAS-related homolog 6 antibody, ARH6 antibody, ARHB antibody, H6 antibody, MST081 antibody, MSTP081 antibody, oncogene RHO H6 antibody, ras homolog family member B antibody, ras homolog gene family, member B antibody, Rho cDNA clone 6 antibody, Rho related GTP binding protein RhoB Precursor antibody, Rho-related GTP-binding protein RhoB antibody, Rhob antibody, RHOB_HUMAN antibody, RHOH6 antibody

UniProt: P62745