SPTLC1 antibody (AA 37-310)

Catalog No. ABIN7168895

This Rabbit Polyclonal antibody specifically detects SPTLC1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for SPTLC1 antibody (AA 37-310) (ABIN7168895)

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPTLC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SPTLC1 Antibody

Binding Specificity: AA 37-310

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Serine palmitoyltransferase 1 protein (37-310AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SPTLC1

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Alternative Name: SPTLC1

Background:

Background: Serine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference.

Aliases: HSAN antibody, HSAN1 antibody, HSN1 antibody, LBC1 antibody, LCB 1 antibody, LCB1 antibody, Long chain base biosynthesis protein 1 antibody, MGC14645 antibody, Serine C palmitoyltransferase antibody, Serine palmitoyl CoA transferase 1 antibody, Serine palmitoyltransferase 1 antibody, Serine palmitoyltransferase long chain base subunit 1 antibody, Serine palmitoyltransferase subunit 1 antibody, Serine-palmitoyl-CoA transferase 1 antibody, SPT 1 antibody, SPT1 antibody, SPTC1_HUMAN antibody, SPTI antibody, SPTLC 1 antibody, SPTLC1 antibody

UniProt: O15269