CDC42BPB antibody (AA 1609-1711)

Catalog No. ABIN7169072

This Rabbit Polyclonal antibody specifically detects CDC42BPB in ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for CDC42BPB antibody (AA 1609-1711) (ABIN7169072)

Target: CDC42BPB (CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC42BPB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CDC42BPB Antibody

Binding Specificity: AA 1609-1711

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Serine/threonine-protein kinase MRCK beta protein (1609-1711AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CDC42BPB

Target: CDC42BPB (CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB))

Alternative Name: CDC42BPB

Background:

Background: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A.

Aliases: CDC42 binding protein kinase beta antibody, CDC42-binding protein kinase beta antibody, CDC42BPB antibody, DMPK like beta antibody, DMPK-like beta antibody, KIAA1124 antibody, MRCK beta antibody, MRCKB_HUMAN antibody, Myotonic dystrophy kinase related CDC42 binding kinase beta antibody, Myotonic dystrophy kinase-related CDC42-binding kinase beta antibody, Myotonic dystrophy protein kinase like beta antibody, Myotonic dystrophy protein kinase-like beta antibody, Serine/threonine protein kinase MRCK beta antibody, Serine/threonine-protein kinase MRCK beta antibody

UniProt: Q9Y5S2