SMO antibody (AA 40-120)

Catalog No. ABIN7224406

The Rabbit Polyclonal anti-SMO antibody is suitable to detect SMO in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for SMO antibody (AA 40-120) (ABIN7224406)

Target: SMO (Smoothened Homolog (Drosophila) (SMO))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMO antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SMO Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-Smo Polyclonal Antibody

Specificity: Smo Polyclonal Antibody detects endogenous levels of Smo protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Smo at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SMO

Target: SMO (Smoothened Homolog (Drosophila) (SMO))

Alternative Name: Smo

Background: SMO, SMOH, Smoothened homolog, SMO, Protein GxThe protein encoded by SMO (smoothened, frizzled class receptor)is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.

Molecular Weight: 86kD

Gene ID: 6608

UniProt: Q99835

Pathways: Hedgehog Signaling