SF3B2 antibody (AA 616-895)

Catalog No. ABIN7170622

The Rabbit Polyclonal anti-SF3B2 antibody (ABIN7170622) specifically detects SF3B2 in IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for SF3B2 antibody (AA 616-895) (ABIN7170622)

Target: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3B2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-SF3B2 Antibody

Binding Specificity: AA 616-895

Purpose: SF3B2 Antibody

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Splicing factor 3B subunit 2 protein (616-895AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SF3B2

Target: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Alternative Name: SF3B2

Background:

Background: Subunit of the splicing factor SF3B required for \\\'A\\\' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the \\\'E\\\' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Aliases: SF3B2 antibody, SAP145 antibody, Splicing factor 3B subunit 2 antibody, Pre-mRNA-splicing factor SF3b 145 kDa subunit antibody, SF3b145 antibody, Spliceosome-associated protein 145 antibody, SAP 145 antibody

UniProt: Q13435