TTBK2 antibody (AA 1185-1244)

Catalog No. ABIN7171585

Product Details anti-TTBK2 Antibody

Target: TTBK2 (tau Tubulin Kinase 2 (TTBK2))

Binding Specificity: AA 1185-1244

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTBK2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Tau-tubulin kinase 2 protein (1185-1244AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TTBK2

Target: TTBK2 (tau Tubulin Kinase 2 (TTBK2))

Alternative Name: TTBK2 (TTBK2 Products)

Synonyms: ttbk antibody, MGC146331 antibody, 2610507N02Rik antibody, AI326283 antibody, B930008N24Rik antibody, TTK antibody, Ttbk antibody, Ttbk1 antibody, mKIAA0847 antibody, SCA11 antibody, TTBK antibody, tau tubulin kinase 2 antibody, TTBK2 antibody, ttbk2 antibody, Ttbk2 antibody

Background:

Background: Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother centriole, leading to the recruitment of IFT proteins, which build the ciliary axoneme. Has some substrate preference for proteins that are already phosphorylated on a Tyr residue at the +2 position relative to the phosphorylation site. Able to phosphorylate tau on serines in vitro.

Aliases: TTBK2 antibody, KIAA0847 antibody, Tau-tubulin kinase 2 antibody, EC 2.7.11.1 antibody

UniProt: Q6IQ55