TANK antibody (AA 4-98) (Biotin)
Quick Overview for TANK antibody (AA 4-98) (Biotin) (ABIN7172329)
Target
See all TANK AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 4-98
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human TRAF family member-associated NF-kappa-B activator protein (4-98AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
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Alternative Name
- TANK
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Background
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Background: Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Acts as a regulator of TRAF function by maintaining them in a latent state. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May control negatively TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2.
Aliases: I TRAF antibody, I-TRAF antibody, ITRAF antibody, Tank antibody, TANK_HUMAN antibody, TRAF family member associated NF KAPPA B activator antibody, TRAF family member associated NFKB activator antibody, TRAF family member-associated NF-kappa-B activator antibody, TRAF interacting protein antibody, TRAF interacting protein TANK isoform a antibody, TRAF interacting protein TANK isoform b antibody, TRAF-interacting protein antibody, TRAF2 antibody
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UniProt
- Q92844
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Pathways
- p53 Signaling, TLR Signaling, Activation of Innate immune Response
Target
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