C-JUN antibody (AA 1-100)

Catalog No. ABIN7172471

This Rabbit Polyclonal antibody specifically detects C-JUN in WB, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for C-JUN antibody (AA 1-100) (ABIN7172471)

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C-JUN antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-C-JUN Antibody

Binding Specificity: AA 1-100

Purpose: JUN Antibody

Cross-Reactivity: Mouse, Rat

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Transcription factor AP-1 protein (1-100AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for C-JUN

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Alternative Name: JUN

Background:

Background: Transcription factor that recognizes and binds to the enhancer heptamer motif 5\\\'-TGA[CG]TCA-3\\\'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).

Aliases: Activator protein 1 antibody, AP 1 antibody, AP-1 antibody, AP1 antibody, cJun antibody, Enhancer Binding Protein AP1 antibody, Jun Activation Domain Binding Protein antibody, JUN antibody, Jun oncogene antibody, JUN protein antibody, Jun proto oncogene antibody, JUN_HUMAN antibody, JUNC antibody, Oncogene JUN antibody, p39 antibody, Proto oncogene c jun antibody, Proto oncogene cJun antibody, Proto-oncogene c-jun antibody, Transcription Factor AP 1 antibody, Transcription factor AP-1 antibody, Transcription Factor AP1 antibody, V jun avian sarcoma virus 17 oncogene homolog antibody, V jun sarcoma virus 17 oncogene homolog (avian) antibody, V jun sarcoma virus 17 oncogene homolog antibody, V-jun avian sarcoma virus 17 oncogene homolog antibody, vJun Avian Sarcoma Virus 17 Oncogene Homolog antibody

UniProt: P05412

Pathways: MAPK Signaling, RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins