TMPRSS6 antibody (AA 98-301) (HRP)

Catalog No. ABIN7173014

Product Details anti-TMPRSS6 Antibody (HRP)

Target: TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))

Binding Specificity: AA 98-301

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS6 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Transmembrane protease serine 6 protein (98-301AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TMPRSS6

Target: TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))

Alternative Name: TMPRSS6 (TMPRSS6 Products)

Synonyms: IRIDA antibody, 1300008A22Rik antibody, transmembrane protease, serine 6 antibody, transmembrane serine protease 6 antibody, Tmprss6 antibody, TMPRSS6 antibody

Background:

Background: Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Through the cleavage of HFE2, a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis.

Aliases: IRIDA antibody, Matriptase-2 antibody, Membrane bound mosaic serine proteinase matriptase 2 antibody, Membrane type serine proteinase 2 antibody, MTSP 2 antibody, MTSP2 antibody, PVAE354 antibody, TMPRSS 6 antibody, TMPRSS6 antibody, TMPS6_HUMAN antibody, TMSP 6 antibody, TMSP6 antibody, Transmembrane protease serine 6 antibody, Type II Membrane Serine Proteinase 6 antibody

UniProt: Q8IU80

Pathways: Transition Metal Ion Homeostasis