RYK antibody (AA 494-586) (Biotin)

Catalog No. ABIN7174061

This Rabbit Polyclonal antibody specifically detects RYK in ELISA. It exhibits reactivity toward Human.

Quick Overview for RYK antibody (AA 494-586) (Biotin) (ABIN7174061)

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RYK antibody is conjugated to Biotin

Application: ELISA

Product Details anti-RYK Antibody (Biotin)

Binding Specificity: AA 494-586

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Tyrosine-protein kinase RYK protein (494-586AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RYK

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Alternative Name: RYK

Background:

Background: May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

Aliases: D3S3195 antibody, ERK 3 antibody, Hydroxyaryl protein kinase antibody, JTK 5 antibody, JTK 5A antibody, JTK5 antibody, JTK5A antibody, JTK5A protein tyrosine kinase antibody, receptor like tyrosine kinase antibody, receptor like tyrosine kinase precursor antibody, RYK 1 antibody, Ryk antibody, RYK_HUMAN antibody, RYK1 antibody, Tyrosine protein kinase RYK antibody, Tyrosine protein kinase RYK precursor antibody, Tyrosine-protein kinase RYK antibody, Vik antibody

UniProt: P34925

Pathways: RTK Signaling, WNT Signaling, Regulation of Cell Size