Ephrin B3 antibody (AA 28-227) (HRP)

Catalog No. ABIN7177180

Product Details anti-Ephrin B3 Antibody (HRP)

Target: Ephrin B3 (EFNB3)

Binding Specificity: AA 28-227

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin B3 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Ephrin-B3 protein (28-227AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Ephrin B3

Target: Ephrin B3 (EFNB3)

Alternative Name: Efnb3 (EFNB3 Products)

Synonyms: efnb3-A antibody, EphB3 antibody, EFNB3 antibody, efnb3 antibody, id:ibd5049 antibody, zgc:111938 antibody, EFL-6 antibody, ELF-3 antibody, Elk-L3 antibody, Epl8 antibody, LERK-8 antibody, NLERK-2 antibody, ELK-L3 antibody, RGD1565678 antibody, EFL6 antibody, EPLG8 antibody, LERK8 antibody, ephrin B3 antibody, ephrin-B3 L homeolog antibody, ephrin-B3b antibody, ephrin-B3 antibody, EFNB3 antibody, efnb3.L antibody, efnb3b antibody, efnb3 antibody, Efnb3 antibody

Background:

Background: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.

Aliases: Efnb3Ephrin-B3 antibody

UniProt: O35393

Pathways: RTK Signaling