CD14 antibody (Biotin)

Catalog No. ABIN7178397

The Mouse Monoclonal anti-CD14 antibody has been validated for FACS, ELISA and IF. It is suitable to detect CD14 in samples from Human.

Quick Overview for CD14 antibody (Biotin) (ABIN7178397)

Target: CD14

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD14 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), ELISA, Immunofluorescence (IF)

Product Details anti-CD14 Antibody (Biotin)

Cross-Reactivity: Human

Purification: Affinity purified

Immunogen: Recombinant Protein

Isotype: IgG1, IgG1 kappa

Application Details

Application Notes: Recommended dilution:IF:1:100-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD14

Target: CD14

Alternative Name: CD14

Background:

Background: 4AW4 reacts with CD14, a 53-55 kDa molecule. CD14 is a human high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS-endotoxin) and serum LPS-binding protein (LPB). CD14 antigen has a strong presence on the surface of monocytes/macrophages, is weakly expressed on granulocytes, but not expressed by myeloid progenitor cells. CD14 functions as a receptor for endotoxin; when the monocytes become activated they release cytokines such as TNF, and up-regulate cell surface molecules including adhesion molecules.This clone is cross reactive with non-human primate.1.  Knapp, W et al., eds. (1989) Leucocyte Typing IV : White Cell Differentiation Antigens, Oxford University Press, New York.2.  Makgoba, MW et al., (1988) Nature 331: 86-883.  Boyd. AW et al. (1989) Blood  73: 1896-1903

Aliases: N/A

UniProt: P08571

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades