CD14 antibody (PE)

Catalog No. ABIN7178399

This Mouse Monoclonal antibody specifically detects CD14 in FACS, IF and ELISA. It exhibits reactivity toward Human.

Quick Overview for CD14 antibody (PE) (ABIN7178399)

Target: CD14

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD14 antibody is conjugated to PE

Application: Flow Cytometry (FACS), Immunofluorescence (IF), ELISA

Product Details anti-CD14 Antibody (PE)

Purpose: CD14 Monoclonal Antibody,PE Conjugated

Purification: Affinity purified

Immunogen: Recombinant Protein

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD14

Target: CD14

Alternative Name: CD14

Background:

Background: 4AW4 reacts with CD14, a 53-55 kDa molecule. CD14 is a human high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS-endotoxin) and serum LPS-binding protein (LPB). CD14 antigen has a strong presence on the surface of monocytes/macrophages, is weakly expressed on granulocytes, but not expressed by myeloid progenitor cells. CD14 functions as a receptor for endotoxin; when the monocytes become activated they release cytokines such as TNF, and up-regulate cell surface molecules including adhesion molecules.This clone is cross reactive with non-human primate.1. Knapp, W et al., eds. (1989)  Leucocyte Typing  IV: White Cell Differentiation Antigens, Oxford University Press, New York.2. Makgoba, MW et al., (1988)  Nature  331: 86-883. Boyd. AW et al. (1989) Blood 73: 1896-1903

Aliases: N/A

UniProt: P08571

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades