NADPH Oxidase 4 antibody (AA 210-424)

Catalog No. ABIN7178969

This Rabbit Polyclonal antibody specifically detects NADPH Oxidase 4 in WB and ELISA. It exhibits reactivity toward Rat.

Quick Overview for NADPH Oxidase 4 antibody (AA 210-424) (ABIN7178969)

Target: NADPH Oxidase 4 (NOX4)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NADPH Oxidase 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NADPH Oxidase 4 Antibody

Binding Specificity: AA 210-424

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Rat NADPH oxidase 4 protein (210-424AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NADPH Oxidase 4

Target: NADPH Oxidase 4 (NOX4)

Alternative Name: Nox4

Background:

Background: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.

Aliases: Nox4 antibody, Kox antibody, NADPH oxidase 4 antibody, EC 1.6.3.- antibody, Kidney oxidase-1 antibody, KOX-1 antibody, Kidney superoxide-producing NADPH oxidase antibody

UniProt: Q924V1

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration