NADPH Oxidase 4 antibody (AA 210-424) (FITC)
Quick Overview for NADPH Oxidase 4 antibody (AA 210-424) (FITC) (ABIN7178971)
Target
See all NADPH Oxidase 4 (NOX4) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 210-424
-
Cross-Reactivity
- Rat
-
Purification
- >95%, Protein G purified
-
Immunogen
- Recombinant Rat NADPH oxidase 4 protein (210-424AA)
-
Isotype
- IgG
-
-
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C,-80 °C
-
Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- NADPH Oxidase 4 (NOX4)
-
Alternative Name
- Nox4
-
Background
-
Background: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
Aliases: Nox4 antibody, Kox antibody, NADPH oxidase 4 antibody, EC 1.6.3.- antibody, Kidney oxidase-1 antibody, KOX-1 antibody, Kidney superoxide-producing NADPH oxidase antibody
-
UniProt
- Q924V1
-
Pathways
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
Target
-