MAP2K3 antibody (Thr222)

Catalog No. ABIN7180041

The Rabbit Polyclonal anti-MAP2K3 antibody has been validated for WB, ELISA and IF. It is suitable to detect MAP2K3 in samples from Human.

Quick Overview for MAP2K3 antibody (Thr222) (ABIN7180041)

Target: MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-MAP2K3 Antibody

Binding Specificity: Thr222

Purpose: MAP2K3 (Ab-222) Antibody

Cross-Reactivity: Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human MAP2K3 around the phosphorylation site of threonine 222 (A-K-T(p)-M-D).

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MAP2K3

Target: MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

Alternative Name: MAP2K3

Background:

Background: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.

Derijard B.,Science 267:682-685(1995).
The MGC Project Team,Genome Res. 14:2121-2127(2004).
Lim S.,J. Biol. Chem. 277:25040-25046(2002).

Aliases: AW212142 antibody, dual specificity mitogen activated protein kinase kinase 3 antibody, Dual specificity mitogen-activated protein kinase kinase 3 antibody, MAP kinase kinase 3 antibody, map2k3 antibody, MAPK ERK kinase 3 antibody, MAPK/ERK kinase 3 antibody, MAPKK 3 antibody, MAPKK3 antibody, MEK 3 antibody, MEK3 antibody, Mitogen activated protein kinase kinase 3 antibody, MKK 3 antibody, MKK3 antibody, mMKK3b antibody, MP2K3_HUMAN antibody, PRKMK 3 antibody, PRKMK3 antibody, protein kinase, mitogen-activated, kinase 3 antibody, SAPK kinase 2 antibody, SAPKK 2 antibody, SAPKK2 antibody, Stress activated protein kinase kinase 2 antibody

UniProt: P46734

Pathways: MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2