MAP2K3 antibody (Thr222)
Quick Overview for MAP2K3 antibody (Thr222) (ABIN7180041)
Target
See all MAP2K3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Thr222
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Cross-Reactivity
- Human, Mouse
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized non-phosphopeptide derived from Human MAP2K3 around the phosphorylation site of threonine 222 (A-K-T(p)-M-D).
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Isotype
- IgG
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Application Notes
- WB:1:500-1:3000, IF:1:50-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
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Alternative Name
- MAP2K3
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Background
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Background: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
Derijard B.,Science 267:682-685(1995).
The MGC Project Team,Genome Res. 14:2121-2127(2004).
Lim S.,J. Biol. Chem. 277:25040-25046(2002).Aliases: AW212142 antibody, dual specificity mitogen activated protein kinase kinase 3 antibody, Dual specificity mitogen-activated protein kinase kinase 3 antibody, MAP kinase kinase 3 antibody, map2k3 antibody, MAPK ERK kinase 3 antibody, MAPK/ERK kinase 3 antibody, MAPKK 3 antibody, MAPKK3 antibody, MEK 3 antibody, MEK3 antibody, Mitogen activated protein kinase kinase 3 antibody, MKK 3 antibody, MKK3 antibody, mMKK3b antibody, MP2K3_HUMAN antibody, PRKMK 3 antibody, PRKMK3 antibody, protein kinase, mitogen-activated, kinase 3 antibody, SAPK kinase 2 antibody, SAPKK 2 antibody, SAPKK2 antibody, Stress activated protein kinase kinase 2 antibody
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UniProt
- P46734
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Pathways
- MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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