CDCA2 antibody (C-Term)

Catalog No. ABIN7180137

The Rabbit Polyclonal anti-CDCA2 antibody has been validated for WB and ELISA. It is suitable to detect CDCA2 in samples from Human.

Quick Overview for CDCA2 antibody (C-Term) (ABIN7180137)

Target: CDCA2 (Cell Division Cycle Associated 2 (CDCA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CDCA2 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human CDCA2.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CDCA2

Target: CDCA2 (Cell Division Cycle Associated 2 (CDCA2))

Alternative Name: CDCA2

Background:

Background: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.

Walker M.G., Curr. Cancer Drug Targets 1:73-83(2001).
Ota T., . Genet. 36:40-45(2004).
Olsen J.V., Cell 127:635-648(2006).

Aliases: CDCA2Cell division cycle-associated protein 2 antibody, Recruits PP1 onto mitotic chromatin at anaphase protein antibody, Repo-Man antibody

UniProt: Q69YH5