Ephrin A3 antibody (C-Term)
Quick Overview for Ephrin A3 antibody (C-Term) (ABIN7180164)
Target
See all Ephrin A3 (EFNA3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Cross-Reactivity
- Human, Mouse, Rat
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from C-terminal of Human EFNA3.
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Isotype
- IgG
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Application Notes
- WB:1:500-1:3000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Ephrin A3 (EFNA3)
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Alternative Name
- EFNA3
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Background
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Background: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling By similarity.
Kozlosky C.J., Oncogene 10:299-306(1995).
Davis S., Science 266:816-819(1994).
Gregory S.G., Nature 441:315-321(2006).Aliases: EFL 2 antibody, EFL-2 antibody, EFL2 antibody, EFN A3 antibody, EFNA 3 antibody, Efna3 antibody, EFNA3_HUMAN antibody, EHK1 L antibody, EHK1 ligand antibody, EHK1-L antibody, EHK1L antibody, EPH related receptor tyrosine kinase ligand 3 antibody, EPH-related receptor tyrosine kinase ligand 3 antibody, Ephrin-A3 antibody, EphrinA3 antibody, EPLG 3 antibody, EPLG3 antibody, LERK 3 antibody, LERK-3 antibody, LERK3 antibody, Ligand of eph related kinase 3 antibody
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UniProt
- P52797
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Pathways
- RTK Signaling
Target
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