Endoglin antibody

Catalog No. ABIN7180718

This Mouse Monoclonal antibody specifically detects Endoglin in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Endoglin antibody (ABIN7180718)

Target: Endoglin (ENG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-Endoglin Antibody

Cross-Reactivity: Human

Purification: Affinity purified

Immunogen: Synthesized peptide derived from human CD105(Endoglin)

Isotype: IgG2b kappa

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: ENG

Background:

Background: Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

Aliases: Endoglin (CD antigen CD105), ENG, END

UniProt: P17813