CDC23 antibody (AA 101-200)

Catalog No. ABIN714041

Product Details anti-CDC23 Antibody

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Binding Specificity: AA 101-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC23 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cdc23

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CDC23

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Alternative Name: Cdc23 (CDC23 Products)

Synonyms: CDC23 antibody, anaphase-promoting complex subunit 8 antibody, zgc:56013 antibody, 6030435O18 antibody, D18Ertd243e antibody, ANAPC8 antibody, APC8 antibody, CUT23 antibody, cell division cycle 23 antibody, cell division cycle protein 23 homolog antibody, anaphase-promoting complex subunit 8 antibody, CDC23 (cell division cycle 23, yeast, homolog) antibody, cell division cycle 23 S homeolog antibody, CDC23 cell division cycle 23 antibody, CDC23 antibody, LOC100162672 antibody, LOC100380698 antibody, APC8 antibody, cdc23 antibody, cdc23.S antibody, Cdc23 antibody

Background:

Synonyms: ANAPC8, Anaphase promoting complex subunit 8, Anaphase-promoting complex subunit 8, Apc 8, APC8, Cdc 23, CDC23, CDC23_HUMAN, cell division cycle 23, Cell division cycle 23 homolog, Cell division cycle protein 23, Cell division cycle protein 23 homolog, Cut23, Cyclosome subunit 8.

Background: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Gene ID: 8697

Pathways: Protein targeting to Nucleus