DECR2 antibody

Catalog No. ABIN7183446

The Rabbit Polyclonal anti-DECR2 antibody has been validated for WB and ELISA. It is suitable to detect DECR2 in samples from Human.

Quick Overview for DECR2 antibody (ABIN7183446)

Target: DECR2 (2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DECR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DECR2 Antibody

Purpose: DECR2 Antibody

Cross-Reactivity: Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human DECR2.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DECR2

Target: DECR2 (2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2))

Alternative Name: DECR2

Background:

Background: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.

De Nys K., Biochim. Biophys. Acta 1533:66-72(2001).
Daniels R.J., Hum. Mol. Genet. 10:339-352(2001).
Ota T., Nat. Genet. 36:40-45(2004).

Aliases: 2 4 dienoyl CoA reductase 2 antibody, 2 4 dienoyl CoA reductase 2 peroxisomal antibody, 2 antibody, 4-dienoyl-CoA reductase 2 antibody, 4-dienoyl-CoA reductase antibody, DECR 2 antibody, Decr2 antibody, DECR2_HUMAN antibody, EC 1.3.1.34 antibody, pDCR antibody, Peroxisomal 2 4 dienoyl CoA reductase antibody, Peroxisomal 2 antibody, SDR17C1 antibody, Short chain dehydrogenase/reductase family 17C member 1 antibody

UniProt: Q9NUI1