DECR2 antibody (N-Term)

Catalog No. ABIN2781322

Product Details anti-DECR2 Antibody

Target: DECR2 (2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DECR2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAQPPPDVEG DDCLPAYRHL FCPDLLRDKV AFITGGGSGI GFRIAEIFMR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against DECR2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DECR2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 292 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DECR2

Target: DECR2 (2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2))

Alternative Name: DECR2 (DECR2 Products)

Synonyms: PDCR antibody, SDR17C1 antibody, zC153C20.5 antibody, zgc:85626 antibody, Dcrakl antibody, putativeperoxisomal24-dienoyl-CoAreductase antibody, 2,4-dienoyl-CoA reductase 2 antibody, 2,4-dienoyl CoA reductase 2, peroxisomal antibody, 2,4-dienoyl-CoA reductase 2 L homeolog antibody, 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal antibody, DECR2 antibody, decr2 antibody, decr2.L antibody, Decr2 antibody

Background: DECR2 is auxiliary enzyme of beta-oxidation. It participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. It catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA and has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
Alias Symbols: AL023881.1, PDCR, SDR17C1
Protein Interaction Partner: PEX5, EP300, UBC, APP, NEDD4L,
Protein Size: 292

Molecular Weight: 32 kDa

Gene ID: 26063

NCBI Accession: NM_020664, NP_065715

UniProt: Q9NUI1