MRPS18C antibody

Catalog No. ABIN7183848

The Rabbit Polyclonal anti-MRPS18C antibody has been validated for ELISA, WB, IHC and IF. It is suitable to detect MRPS18C in samples from Human.

Quick Overview for MRPS18C antibody (ABIN7183848)

Target: MRPS18C (Mitochondrial Ribosomal Protein S18C (MRPS18C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS18C antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPS18C Antibody

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human MRPS18C.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MRPS18C

Target: MRPS18C (Mitochondrial Ribosomal Protein S18C (MRPS18C))

Alternative Name: MRPS18C

Background:

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q.

Lai C.-H., Genome Res. 10:703-713(2000).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Koc E.C., J. Biol. Chem. 276:19363-19374(2001).

Aliases: MRPS18C antibody, CGI-134 antibody, 28S ribosomal protein S18c antibody, mitochondrial antibody, MRP-S18-c antibody, Mrps18-c antibody, S18mt-c antibody, 28S ribosomal protein S18-1 antibody, mitochondrial antibody, MRP-S18-1 antibody, Mitochondrial small ribosomal subunit protein bS18c antibody, Mitochondrial small ribosomal subunit protein bS18m antibody

UniProt: Q9Y3D5