TLE2 antibody

Catalog No. ABIN7184265

Product Details anti-TLE2 Antibody

Target: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human TLE2.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TLE2

Target: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Alternative Name: TLE2 (TLE2 Products)

Synonyms: TLE2 antibody, ESG antibody, ESG2 antibody, GRG2 antibody, Grg2 antibody, mKIAA4188 antibody, transducin like enhancer of split 2 antibody, transducin-like enhancer of split 2 antibody, TLE2 antibody, Tle2 antibody

Background:

Background: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES By similarity.

Stifani S., Nat. Genet. 2:119-127(1992).
Grimwood J., Nature 428:529-535(2004).
Grbavec D., Eur. J. Biochem. 258:339-349(1998).

Aliases: enhancer of split groucho 2 antibody, enhancer of split groucho 2 antibody, Enhancer of split groucho-like protein 2 antibody, ESG antibody, ESG2 antibody, FLJ41188 antibody, GRG2 antibody, Groucho2 antibody, KIAA4188 antibody, MGC124808 antibody, mKIAA4188 antibody, Tle2 antibody, Tle2 protein antibody, TLE2_HUMAN antibody, transducin like enhancer of split 2 antibody, Transducin like enhancer of split 2, homolog of Drosophila E(sp1) antibody, Transducin like enhancer protein 2 antibody, Transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) antibody, Transducin-like enhancer of split 2, homolog of Drosophila E(spl) antibody, Transducin-like enhancer protein 2 antibody

UniProt: Q04725

Pathways: WNT Signaling