HLA-DOB antibody (N-Term)

Catalog No. ABIN7184461

The Rabbit Polyclonal anti-HLA-DOB antibody (ABIN7184461) specifically detects HLA-DOB in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for HLA-DOB antibody (N-Term) (ABIN7184461)

Target: HLA-DOB (Major Histocompatibility Complex, Class II, DO beta (HLA-DOB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLA-DOB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HLA-DOB Antibody

Binding Specificity: N-Term

Purpose: HLA-DOB Antibody

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human HLA-DOB.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HLA-DOB

Target: HLA-DOB (Major Histocompatibility Complex, Class II, DO beta (HLA-DOB))

Alternative Name: HLA-DOB

Background:

Background: Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.

Tonnelle C., EMBO J. 4:2839-2847(1985).
Jonsson A.-K., Immunogenetics 29:411-413(1989).
Beck S., J. Mol. Biol. 228:433-441(1992).

Aliases: HLA-DOBHLA class II histocompatibility antigen antibody, DO beta chain antibody, MHC class II antigen DOB antibody

UniProt: P13765

Pathways: Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response