MARK3 antibody (N-Term)

Catalog No. ABIN7184477

This Rabbit Polyclonal antibody specifically detects MARK3 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for MARK3 antibody (N-Term) (ABIN7184477)

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MARK3 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human MARK3.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MARK3

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Alternative Name: MARK3

Background:

Background: Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.

Peng C.Y., Cell Growth Differ. 9:197-208(1998).
Sun T.-Q., Nat. Cell Biol. 3:628-636(2001).
Wissing J., Mol. Cell. Proteomics 6:537-547(2007)

Aliases: C-TAK1 antibody, Cdc25C associated protein kinase 1 antibody, Cdc25C-associated protein kinase 1 antibody, cTAK1 antibody, ELKL motif kinase 2 antibody, EMK-2 antibody, Emk2 antibody, ETK 1 antibody, KIAA4230 antibody, KP78 antibody, MAP microtubule affinity regulating kinase 3 antibody, MAP/microtubule affinity-regulating kinase 3 antibody, Mark3 antibody, MARK3_HUMAN antibody, Par 1a antibody, PAR1A antibody, Protein kinase STK10 antibody, Ser/Thr protein kinase PAR-1 antibody, Serine threonine protein kinase p78 antibody, Serine/threonine-protein kinase p78 antibody, SerThr protein kinase PAR 1 antibody

UniProt: P27448

Pathways: SARS-CoV-2 Protein Interactome